Description：

NMS-P937 (NMS1286937) is an orally available, selective Polo-like Kinase 1 (PLK1) inhibitor with IC50 of 2 nM, 5000-fold selectivity over PLK2/PLK3. Phase 1.

Chemical Information：

Molecular Weight (MW)		532.52
Formula		C24H27F3N8O3
CAS No.		1034616-18-6
Solubility (25°C) *	DMSO	42 mg/mL warmed (78.87 mM)
	Water	Insoluble
	Alcohol	10 mg/mL warmed (18.77 mM)

Preparing Stock Solutions

Concentration Volume (DMSO) Mass	1 mg	5 mg	10 mg
1 mM	1.8779 mL	9.3893 mL	18.7786 mL
5 mM	0.3756 mL	1.8779 mL	3.7557 mL
10 mM	0.1878 mL	0.9389 mL	1.8779 mL
50 mM	0.0376 mL	0.1878 mL	0.3756 mL

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