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Description:
NMS-873 is an allosteric and specific p97 inhibitor with IC50 of 30 nM that demonstrates potent selectivity for VCP/p97 compared to a panel of other AAA ATPases, Hsp90, and 53 additional analyzed kinases (IC50s >10 μM).
Chemical Information:
Molecular Weight (MW) 520.67 Formula
C27H28N4O3S2
CAS No. 1418013-75-8 Solubility (25°C) * DMSO 100 mg/mL (192.06 mM) Water Insoluble Alcohol Insoluble
Preparing Stock Solutions
Concentration Volume (DMSO) Mass 1 mg 5 mg 10 mg 1 mM 1.9206 mL 9.6030 mL 19.2060 mL 5 mM 0.3841 mL 1.9206 mL 3.8412 mL 10 mM 0.1921 mL 0.9603 mL 1.9206 mL 50 mM 0.0384 mL 0.1921 mL 0.3841 mL
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