Description：

Nintedanib (BIBF 1120) is a potent triple angiokinase inhibitor for VEGFR1/2/3, FGFR1/2/3 and PDGFRα/β with IC50 of 34 nM/13 nM/13 nM, 69 nM/37 nM/108 nM and 59 nM/65 nM in cell-free assays. Phase 3.

Chemical Information：

Molecular Weight (MW)		539.62
Formula		C31H33N5O4
CAS No.		656247-17-5
Solubility (25°C) *	DMSO	6 mg/mL (11.11 mM)
	Water	Insoluble
	Alcohol	3 mg/mL (5.55 mM)

Preparing Stock Solutions

Concentration Volume (DMSO) Mass	1 mg	5 mg	10 mg
1 mM	1.8532 mL	9.2658 mL	18.5316 mL
5 mM	0.3706 mL	1.8532 mL	3.7063 mL
10 mM	0.1853 mL	0.9266 mL	1.8532 mL
50 mM	0.0371 mL	0.1853 mL	0.3706 mL

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