Description：

APTSTAT3-9R is a specific STAT3-binding peptide with addition of a cell-penetrating motif. The treatment of APTSTAT3-9R in various types of cancer cells blocks STAT3 phosphorylation and reduces expression of STAT targets.

Chemical Information：

Molecular Weight (MW)		4947.51
Formula		C223H330N80O51
CAS No.
Solubility (25°C) *	DMSO
	Water	98 mg/mL (19.8 mM)
	Alcohol

Biological Activity：

Targets IC50

CDK2/Cyclin E CDK5/p25 CDK9/Cyclin T CDK1/Cyclin B1 CDK6/Cyclin CDK4/Cyclin D1 170 nM 170 nM 20 nM 30 nM 80 nM 100 nM

Preparing Stock Solutions

Concentration Volume (DMSO) Mass	1 mg	5 mg	10 mg
1 mM	0.2021 mL	1.0106 mL	2.0212 mL
5 mM	0.0404 mL	0.2021 mL	0.4042 mL
10 mM	0.0202 mL	0.1011 mL	0.2021 mL
50 mM	-	-	-

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