Description：

Niclosamide can inhibit DNA replication and inhibit STAT3 with IC50 of 0.7 μM in a cell-free assay. Niclosamide selectively inhibited the phosphorylation of STAT3 and had no obvious inhibition against the activation of other homologues (e.g., STAT1 and STAT5).

Chemical Information：

Molecular Weight (MW)		327.12
Formula		C13H8Cl2N2O4
CAS No.		50-65-7
Solubility (25°C) *	DMSO	Insoluble
	Water	Insoluble
	Alcohol

Preparing Stock Solutions

Concentration Volume (DMSO) Mass	1 mg	5 mg	10 mg
1 mM	3.0570 mL	15.2849 mL	30.5698 mL
5 mM	0.6114 mL	3.0570 mL	6.1140 mL
10 mM	0.3057 mL	1.5285 mL	3.0570 mL
50 mM	0.0611 mL	0.3057 mL	0.6114 mL

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