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Description:
APS-2-79 is a MAPK antagonist that modulating KSR-dependent MAPK signalling by antagonizing RAF heterodimerization as well as the conformational changes required for phosphorylation and activation of KSR-bound MEK.
Chemical Information:
Molecular Weight (MW) 423.89 Formula
C23H21N3O3.HCl
CAS No. 2002381-31-7 Solubility (25°C) * DMSO 97 mg/mL (228.83 mM) Water Insoluble Alcohol 32 mg/mL (75.49 mM)
Preparing Stock Solutions
Concentration Volume (DMSO) Mass 1 mg 5 mg 10 mg 1 mM 2.3591 mL 11.7955 mL 23.5910 mL 5 mM 0.4718 mL 2.3591 mL 4.7182 mL 10 mM 0.2359 mL 1.1796 mL 2.3591 mL 50 mM 0.0472 mL 0.2359 mL 0.4718 mL
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