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Description:
Apoptosis Activator 2 strongly induces caspase-3 activation, PARP cleavage, and DNA fragmentation which leads to the destruction of cells (Apaf-1 dependent) with IC50 of ~4 μM, inactive to HMEC, PREC, or MCF-10A cells.
Chemical Information:
Molecular Weight (MW) 306.14 Formula
C15H9Cl2NO2
CAS No. 79183-19-0 Solubility (25°C) * DMSO 61 mg/mL (199.25 mM) Water Insoluble Alcohol Insoluble
Preparing Stock Solutions
Concentration Volume (DMSO) Mass 1 mg 5 mg 10 mg 1 mM 3.2665 mL 16.3324 mL 32.6648 mL 5 mM 0.6533 mL 3.2665 mL 6.5330 mL 10 mM 0.3266 mL 1.6332 mL 3.2665 mL 50 mM 0.0653 mL 0.3266 mL 0.6533 mL
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