Description：

Motolimod (VTX-2337) is a selective and potent Toll-like receptor (TLR) 8 agonist with EC50 of 100 nM, > 50-fold selectivity over TLR7. Phase 2.

Chemical Information：

Molecular Weight (MW)		458.6
Formula		C28H34N4O2
CAS No.		926927-61-9
Solubility (25°C) *	DMSO	55 mg/mL warmed (119.93 mM)
	Water	Insoluble
	Alcohol	15 mg/mL (32.7 mM)

Preparing Stock Solutions

Concentration Volume (DMSO) Mass	1 mg	5 mg	10 mg
1 mM	2.1805 mL	10.9027 mL	21.8055 mL
5 mM	0.4361 mL	2.1805 mL	4.3611 mL
10 mM	0.2181 mL	1.0903 mL	2.1805 mL
50 mM	0.0436 mL	0.2181 mL	0.4361 mL

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