Description：

Momelotinib (CYT387) is an ATP-competitive inhibitor of JAK1/JAK2 with IC50 of 11 nM/18 nM, ~10-fold selectivity versus JAK3. Phase 3.

Chemical Information：

Molecular Weight (MW)		414.46
Formula		C23H22N6O2
CAS No.		1056634-68-4
Solubility (25°C) *	DMSO	74 mg/mL (178.54 mM)
	Water	Insoluble
	Alcohol	Insoluble

Preparing Stock Solutions

Concentration Volume (DMSO) Mass	1 mg	5 mg	10 mg
1 mM	2.4128 mL	12.0639 mL	24.1278 mL
5 mM	0.4826 mL	2.4128 mL	4.8256 mL
10 mM	0.2413 mL	1.2064 mL	2.4128 mL
50 mM	0.0483 mL	0.2413 mL	0.4826 mL

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