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Description:
Mocetinostat (MGCD0103) is a potent HDAC inhibitor with most potency for HDAC1 with IC50 of 0.15 μM in a cell-free assay, 2- to 10- fold selectivity against HDAC2, 3, and 11, and no activity to HDAC4, 5, 6, 7, and 8. Phase 2.
Chemical Information:
Molecular Weight (MW) 396.44 Formula
C23H20N6O
CAS No. 726169-73-9 Solubility (25°C) * DMSO 13 mg/mL (32.79 mM) Water Insoluble Alcohol Insoluble
Preparing Stock Solutions
Concentration Volume (DMSO) Mass 1 mg 5 mg 10 mg 1 mM 2.5224 mL 12.6122 mL 25.2245 mL 5 mM 0.5045 mL 2.5224 mL 5.0449 mL 10 mM 0.2522 mL 1.2612 mL 2.5224 mL 50 mM 0.0504 mL 0.2522 mL 0.5045 mL
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