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Description:
MLN8054 is a potent and selective inhibitor of Aurora A with IC50 of 4 nM in Sf9 insect cell. It is more than 40-fold selective for Aurora A than Aurora B. Phase 1.
Chemical Information:
Molecular Weight (MW) 476.86 Formula
C25H15ClF2N4O2
CAS No. 869363-13-3 Solubility (25°C) * DMSO 95 mg/mL (199.21 mM) Water Insoluble Alcohol Insoluble
Preparing Stock Solutions
Concentration Volume (DMSO) Mass 1 mg 5 mg 10 mg 1 mM 2.0971 mL 10.4853 mL 20.9705 mL 5 mM 0.4194 mL 2.0971 mL 4.1941 mL 10 mM 0.2097 mL 1.0485 mL 2.0971 mL 50 mM 0.0419 mL 0.2097 mL 0.4194 mL
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