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Description:
MK-8776 (SCH 900776) is a selective Chk1 inhibitor with IC50 of 3 nM in a cell-free assay. It shows 500-fold selectivity against Chk2. Phase 2.
Chemical Information:
Molecular Weight (MW) 376.25 Formula
C15H18BrN7
CAS No. 891494-63-6 Solubility (25°C) * DMSO 3 mg/mL (7.97 mM) Water Insoluble Alcohol Insoluble
Preparing Stock Solutions
Concentration Volume (DMSO) Mass 1 mg 5 mg 10 mg 1 mM 2.6578 mL 13.2890 mL 26.5781 mL 5 mM 0.5316 mL 2.6578 mL 5.3156 mL 10 mM 0.2658 mL 1.3289 mL 2.6578 mL 50 mM 0.0532 mL 0.2658 mL 0.5316 mL
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