Description：

MK-8745 is a potent and selective Aurora A inhibitor with IC50 of 0.6 nM, more than 450-fold selectivity for Aurora A over Aurora B.

Chemical Information：

Molecular Weight (MW)		431.91
Formula		C20 H19 Cl F N5 O S
CAS No.		885325-71-3
Solubility (25°C) *	DMSO	86 mg/mL (199.11 mM)
	Water	Insoluble
	Alcohol	1 mg/mL (2.31 mM)

Preparing Stock Solutions

Concentration Volume (DMSO) Mass	1 mg	5 mg	10 mg
1 mM	2.3153 mL	11.5765 mL	23.1530 mL
5 mM	0.4631 mL	2.3153 mL	4.6306 mL
10 mM	0.2315 mL	1.1576 mL	2.3153 mL
50 mM	0.0463 mL	0.2315 mL	0.4631 mL

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