Description：

MK-2206 2HCl is a highly selective inhibitor of Akt1/2/3 with IC50 of 8 nM/12 nM/65 nM in cell-free assays, respectively; no inhibitory activities against 250 other protein kinases observed. Phase 2.

Chemical Information：

Molecular Weight (MW)		480.39
Formula		C25H21N5O.2HCl
CAS No.		1032350-13-2
Solubility (25°C) *	DMSO	14 mg/mL (29.14 mM)
	Water	Insoluble
	Alcohol	Insoluble

Preparing Stock Solutions

Concentration Volume (DMSO) Mass	1 mg	5 mg	10 mg
1 mM	2.0816 mL	10.4082 mL	20.8164 mL
5 mM	0.4163 mL	2.0816 mL	4.1633 mL
10 mM	0.2082 mL	1.0408 mL	2.0816 mL
50 mM	0.0416 mL	0.2082 mL	0.4163 mL

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