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Description:
MK-0752 is a moderately potent γ-secretase inhibitor, which reduces Aβ40 production with IC50 of 5 nM. Phase 1/2.
Chemical Information:
Molecular Weight (MW) 442.9 Formula
C21H21ClF2O4S
CAS No. 471905-41-6 Solubility (25°C) * DMSO 89 mg/mL (200.94 mM) Water Insoluble Alcohol 45 mg/mL (101.6 mM)
Preparing Stock Solutions
Concentration Volume (DMSO) Mass 1 mg 5 mg 10 mg 1 mM 2.2578 mL 11.2892 mL 22.5785 mL 5 mM 0.4516 mL 2.2578 mL 4.5157 mL 10 mM 0.2258 mL 1.1289 mL 2.2578 mL 50 mM 0.0452 mL 0.2258 mL 0.4516 mL
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