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MK-0752

MK-0752

Catalog Number: CC2816 Rank: comment rank 5

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Description:

MK-0752 is a moderately potent γ-secretase inhibitor, which reduces Aβ40 production with IC50 of 5 nM. Phase 1/2.

Chemical Information:

Molecular Weight (MW) 442.9
Formula

 

C21H21ClF2O4S

 

CAS No. 471905-41-6
Solubility (25°C) * DMSO 89 mg/mL (200.94 mM)
Water Insoluble
Alcohol 45 mg/mL (101.6 mM)


Preparing Stock Solutions

Concentration Volume (DMSO) Mass 1 mg 5 mg 10 mg
1 mM 2.2578 mL 11.2892 mL 22.5785 mL
5 mM 0.4516 mL 2.2578 mL 4.5157 mL
10 mM 0.2258 mL 1.1289 mL 2.2578 mL
50 mM 0.0452 mL 0.2258 mL 0.4516 mL


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