Description：

Apalutamide (ARN-509) is a selective and competitive androgen receptor inhibitor with IC50 of 16 nM in a cell-free assay, useful for prostate cancer treatment. Phase 3.

Chemical Information：

Molecular Weight (MW)		477.43
Formula		C21H15F4N5O2S
CAS No.		956104-40-8
Solubility (25°C) *	DMSO	18 mg/mL (37.7 mM)
	Water	Insoluble
	Alcohol	5 mg/mL (10.47 mM)

Biological Activity：

Targets IC50

UT-SCC-19A cells 4 nM

Preparing Stock Solutions

Concentration Volume (DMSO) Mass	1 mg	5 mg	10 mg
1 mM	2.0945 mL	10.4727 mL	20.9455 mL
5 mM	0.4189 mL	2.0945 mL	4.1891 mL
10 mM	0.2095 mL	1.0473 mL	2.0945 mL
50 mM	0.0419 mL	0.2095 mL	0.4189 mL

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