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Description:
Miltefosine inhibits PI3K/Akt activity with ED50 of 17.2 μM and 8.1 μM in carcinoma cell lines A431 and HeLa, first oral drug for Visceral leishmaniasis, effective against both promastigotes and amastigotes.
Chemical Information:
Molecular Weight (MW) 407.57 Formula
C21H46NO4P
CAS No. 58066-85-6 Solubility (25°C) * DMSO Insoluble Water 81 mg/mL (198.73 mM) Alcohol 81 mg/mL (198.73 mM)
Preparing Stock Solutions
Concentration Volume (DMSO) Mass 1 mg 5 mg 10 mg 1 mM 2.4536 mL 12.2678 mL 24.5357 mL 5 mM 0.4907 mL 2.4536 mL 4.9071 mL 10 mM 0.2454 mL 1.2268 mL 2.4536 mL 50 mM 0.0491 mL 0.2454 mL 0.4907 mL
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