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Description:
Milciclib (PHA-848125) is a potent, ATP-competitive CDK inhibitor for CDK2 with IC50 of 45 nM. It is >3-fold more selective for CDK2 than CDK1, 2, 4, 5, and 7. Phase 2.
Chemical Information:
Molecular Weight (MW) 460.57 Formula
C25H32N8O
CAS No. 802539-81-7 Solubility (25°C) * DMSO 92 mg/mL (199.75 mM) Water Insoluble Alcohol Insoluble
Preparing Stock Solutions
Concentration Volume (DMSO) Mass 1 mg 5 mg 10 mg 1 mM 2.1712 mL 10.8561 mL 21.7122 mL 5 mM 0.4342 mL 2.1712 mL 4.3424 mL 10 mM 0.2171 mL 1.0856 mL 2.1712 mL 50 mM 0.0434 mL 0.2171 mL 0.4342 mL
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