Description：

Midostaurin (pkc412) is a multi-targeted kinase inhibitor, including PKCα/β/γ, Syk, Flk-1, Akt, PKA, c-Kit, c-Fgr, c-Src, FLT3, PDFRβ and VEGFR1/2 with IC50 ranging from 80-500 nM.

Chemical Information：

Molecular Weight (MW)		570.64
Formula		C35H30N4O4
CAS No.		120685-11-2
Solubility (25°C) *	DMSO	100 mg/mL (175.24 mM)
	Water	Insoluble
	Alcohol	20 mg/mL warmed (35.04 mM)

Preparing Stock Solutions

Concentration Volume (DMSO) Mass	1 mg	5 mg	10 mg
1 mM	1.7524 mL	8.7621 mL	17.5242 mL
5 mM	0.3505 mL	1.7524 mL	3.5048 mL
10 mM	0.1752 mL	0.8762 mL	1.7524 mL
50 mM	0.0350 mL	0.1752 mL	0.3505 mL

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