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Description:
MGCD-265 is a potent, multi-target and ATP-competitive inhibitor of c-Met and VEGFR1/2/3 with IC50 of 1 nM, 3 nM/3 nM/4 nM, respectively; also inhibits Ron and Tie2. Phase 1/2.
Chemical Information:
Molecular Weight (MW) 517.60 Formula
C26H20FN5O2S2
CAS No. 875337-44-3 Solubility (25°C) * DMSO 104 mg/mL (200.92 mM) Water Insoluble Alcohol Insoluble
Preparing Stock Solutions
Concentration Volume (DMSO) Mass 1 mg 5 mg 10 mg 1 mM 1.9320 mL 9.6600 mL 19.3199 mL 5 mM 0.3864 mL 1.9320 mL 3.8640 mL 10 mM 0.1932 mL 0.9660 mL 1.9320 mL 50 mM 0.0386 mL 0.1932 mL 0.3864 mL
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