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Immunology & Inflammation related inhibitor >
MCC950(CP-456773)
Description:
MCC950 sodium salt is a potent, selective inhibitor of NLRP3 with IC50 of 7.5 nM in BMDMs; but not the AIM2, NLRC4 or NLRP1 inflammasomes.
Chemical Information:
Molecular Weight (MW) 426.46 Formula
C20H23N2O5S.Na
CAS No. 256373-96-3 Solubility (25°C) * DMSO Insoluble Water 85 mg/mL (199.31 mM) Alcohol 40 mg/mL (93.79 mM)
Preparing Stock Solutions
Concentration Volume (DMSO) Mass 1 mg 5 mg 10 mg 1 mM 2.3449 mL 11.7244 mL 23.4489 mL 5 mM 0.4690 mL 2.3449 mL 4.6898 mL 10 mM 0.2345 mL 1.1724 mL 2.3449 mL 50 mM 0.0469 mL 0.2345 mL 0.4690 mL
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