Description：

Marinopyrrole A (Maritoclax) is a selective Mcl-1 antagonist. It binds to Mcl-1, but not Bcl-XL, and targets Mcl-1 for proteasomal degradation. Maritoclax disrupts the interaction between Bim and Mcl-1 with an IC50 of 10.1 μM.

Chemical Information：

Molecular Weight (MW)		510.15
Formula		C22H12Cl4N2O4
CAS No.		1227962-62-0
Solubility (25°C) *	DMSO	100 mg/mL (196.02 mM)
	Water	Insoluble
	Alcohol	45 mg/mL (88.2 mM)

Preparing Stock Solutions

Concentration Volume (DMSO) Mass	1 mg	5 mg	10 mg
1 mM	1.9602 mL	9.8010 mL	19.6021 mL
5 mM	0.3920 mL	1.9602 mL	3.9204 mL
10 mM	0.1960 mL	0.9801 mL	1.9602 mL
50 mM	0.0392 mL	0.1960 mL	0.3920 mL

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