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Description:
3-Methyladenine (3-MA) is a selective PI3K inhibitor for Vps34 and PI3Kγ with IC50 of 25 μM and 60 μM in HeLa cells; blocks class I PI3K consistently, whereas suppression of class III PI3K is transient, and also blocks autophagosome formation.
Chemical Information:
Molecular Weight (MW) 149.15 Formula
C6H7N5
CAS No. 5142-23-4 Solubility (25°C) * DMSO 3 mg/mL warmed (20.11 mM) Water 10 mg/mL warmed (67.04 mM) Alcohol 4 mg/mL (26.81 mM)
Preparing Stock Solutions
Concentration Volume (DMSO) Mass 1 mg 5 mg 10 mg 1 mM 6.7047 mL 33.5233 mL 67.0466 mL 5 mM 1.3409 mL 6.7047 mL 13.4093 mL 10 mM 0.6705 mL 3.3523 mL 6.7047 mL 50 mM 0.1341 mL 0.6705 mL 1.3409 mL
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