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LY294002

LY294002

Catalog Number: CC1261 Rank: comment rank 5

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Description:

LY294002 is the first synthetic molecule known to inhibit PI3Kα/δ/β with IC50 of 0.5 μM/0.57 μM/0.97 μM in cell-free assays, respectively; more stable in solution than Wortmannin, and also blocks autophagosome formation.

Chemical Information:

Molecular Weight (MW) 307.34
Formula

 

C19H17NO3

 

CAS No. 154447-36-6
Solubility (25°C) * DMSO 36 mg/mL (117.13 mM)
Water Insoluble
Alcohol 21 mg/mL (68.32 mM)


Preparing Stock Solutions

Concentration Volume (DMSO) Mass 1 mg 5 mg 10 mg
1 mM 3.2537 mL 16.2686 mL 32.5373 mL
5 mM 0.6507 mL 3.2537 mL 6.5075 mL
10 mM 0.3254 mL 1.6269 mL 3.2537 mL
50 mM 0.0651 mL 0.3254 mL 0.6507 mL


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