Description：

Anacetrapib (MK0859) is a potent, selective, reversible rhCETP and mutant CETP(C13S) inhibitor with IC50 of 7.9 nM and 11.8 nM, increases HDL-C and decreases LDL-C, does not increase aldosterone or blood pressure. Phase 3.

Chemical Information：

Molecular Weight (MW)		637.51
Formula		C30H25F10NO3
CAS No.		875446-37-0
Solubility (25°C) *	DMSO	127 mg/mL (199.21 mM)
	Water	Insoluble
	Alcohol	127 mg/mL (199.21 mM)

Biological Activity：

Targets IC50

HER2 HDAC EGFR 15.7 nM 4.4 nM 2.4 nM

Preparing Stock Solutions

Concentration Volume (DMSO) Mass	1 mg	5 mg	10 mg
1 mM	1.5686 mL	7.8430 mL	15.6860 mL
5 mM	0.3137 mL	1.5686 mL	3.1372 mL
10 mM	0.1569 mL	0.7843 mL	1.5686 mL
50 mM	0.0314 mL	0.1569 mL	0.3137 mL

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