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LY2228820

LY2228820

Catalog Number: CC1650 Rank: comment rank 5

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Description:

LY2228820 is a novel and potent inhibitor of p38 MAPK with IC50 of 7 nM in a cell-free assay, does not alter p38 MAPK activation. Phase 1/2.

Chemical Information:

Molecular Weight (MW) 612.74
Formula

 

C24H29FN6.2CH4O3S

 

CAS No. 862507-23-1
Solubility (25°C) * DMSO 4 mg/mL warmed (6.52 mM)
Water 100 mg/mL warmed (163.2 mM)
Alcohol 3 mg/mL (4.89 mM)


Preparing Stock Solutions

Concentration Volume (DMSO) Mass 1 mg 5 mg 10 mg
1 mM 1.6320 mL 8.1601 mL 16.3201 mL
5 mM 0.3264 mL 1.6320 mL 3.2640 mL
10 mM 0.1632 mL 0.8160 mL 1.6320 mL
50 mM 0.0326 mL 0.1632 mL 0.3264 mL


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