Description：

LY2109761 is a novel selective TGF-β receptor type I/II (TβRI/II) dual inhibitor with K_i of 38 nM and 300 nM in a cell-free assay, respectively; shown to negatively affect the phosphorylation of Smad2.

Chemical Information：

Molecular Weight (MW)		441.52
Formula		C26H27N5O2
CAS No.		700874-71-1
Solubility (25°C) *	DMSO	2 mg/mL (4.52 mM)
	Water	Insoluble
	Alcohol	Insoluble

Preparing Stock Solutions

Concentration Volume (DMSO) Mass	1 mg	5 mg	10 mg
1 mM	2.2649 mL	11.3245 mL	22.6490 mL
5 mM	0.4530 mL	2.2649 mL	4.5298 mL
10 mM	0.2265 mL	1.1325 mL	2.2649 mL
50 mM	0.0453 mL	0.2265 mL	0.4530 mL

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