Description：

LY2090314 is a potent GSK-3 inhibitor for GSK-3α/β with IC50 of 1.5 nM/0.9 nM; may improve the efficacy of platinum-based chemotherapy regimens. LY2090314 is highly selective towards GSK3 as demonstrated by its fold selectivity relative to a large panel of kinases.

Chemical Information：

Molecular Weight (MW)		512.53
Formula		C28H25FN6O3
CAS No.		603288-22-8
Solubility (25°C) *	DMSO	100 mg/mL (195.11 mM)
	Water	Insoluble
	Alcohol	2 mg/mL warmed (3.9 mM)

Preparing Stock Solutions

Concentration Volume (DMSO) Mass	1 mg	5 mg	10 mg
1 mM	1.9511 mL	9.7555 mL	19.5111 mL
5 mM	0.3902 mL	1.9511 mL	3.9022 mL
10 mM	0.1951 mL	0.9756 mL	1.9511 mL
50 mM	0.0390 mL	0.1951 mL	0.3902 mL

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