Description：

ANA-12 is a selective TrkB antagonist with K_d of 10 nM and 12 μM for the high and low affinity sites, respectively.

Chemical Information：

Molecular Weight (MW)		407.49
Formula		C22H21N3O3S
CAS No.		219766-25-3
Solubility (25°C) *	DMSO	37 mg/mL warmed (90.79 mM)
	Water	Insoluble
	Alcohol	Insoluble

Biological Activity：

Targets IC50

AR 0.16 μM

Preparing Stock Solutions

Concentration Volume (DMSO) Mass	1 mg	5 mg	10 mg
1 mM	2.4540 mL	12.2702 mL	24.5405 mL
5 mM	0.4908 mL	2.4540 mL	4.9081 mL
10 mM	0.2454 mL	1.2270 mL	2.4540 mL
50 mM	0.0491 mL	0.2454 mL	0.4908 mL

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