Description：

Losmapimod (GW856553X) is a selective, potent, and orally active p38 MAPK inhibitor with pK_i of 8.1 and 7.6 for p38α and p38β, respectively. Phase 3.

Chemical Information：

Molecular Weight (MW)		383.46
Formula		C22 H26 F N3 O2
CAS No.		585543-15-3
Solubility (25°C) *	DMSO	76 mg/mL (198.19 mM)
	Water	Insoluble
	Alcohol	41 mg/mL warmed (106.92 mM)

Preparing Stock Solutions

Concentration Volume (DMSO) Mass	1 mg	5 mg	10 mg
1 mM	2.6078 mL	13.0392 mL	26.0783 mL
5 mM	0.5216 mL	2.6078 mL	5.2157 mL
10 mM	0.2608 mL	1.3039 mL	2.6078 mL
50 mM	0.0522 mL	0.2608 mL	0.5216 mL

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