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Description:
Amuvatinib (MP-470) is a potent and multi-targeted inhibitor of c-Kit, PDGFRα and Flt3 with IC50 of 10 nM, 40 nM and 81 nM, respectively. Phase 2.
Chemical Information:
Molecular Weight (MW) 447.51 Formula
C23H21N5O3S
CAS No. 850879-09-3 Solubility (25°C) * DMSO 32 mg/mL (71.5 mM) Water Insoluble Alcohol Insoluble
Biological Activity:
Targets IC50
aromatase 15 nM
Preparing Stock Solutions
Concentration Volume (DMSO) Mass 1 mg 5 mg 10 mg 1 mM 2.2346 mL 11.1729 mL 22.3459 mL 5 mM 0.4469 mL 2.2346 mL 4.4692 mL 10 mM 0.2235 mL 1.1173 mL 2.2346 mL 50 mM 0.0447 mL 0.2235 mL 0.4469 mL
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