Description：

Linifanib (ABT-869) is a novel, potent ATP-competitive VEGFR/PDGFR inhibitor for KDR, CSF-1R, Flt-1/3 and PDGFRβ with IC50 of 4 nM, 3 nM, 3 nM/4 nM and 66 nM respectively, mostly effective in mutant kinase-dependent cancer cells (i.e. FLT3). Phase 3.

Chemical Information：

Molecular Weight (MW)		375.41
Formula		C21H18FN5O
CAS No.		796967-16-3
Solubility (25°C) *	DMSO	75 mg/mL (199.78 mM)
	Water	Insoluble
	Alcohol	Insoluble

Preparing Stock Solutions

Concentration Volume (DMSO) Mass	1 mg	5 mg	10 mg
1 mM	2.6638 mL	13.3188 mL	26.6375 mL
5 mM	0.5328 mL	2.6638 mL	5.3275 mL
10 mM	0.2664 mL	1.3319 mL	2.6638 mL
50 mM	0.0533 mL	0.2664 mL	0.5328 mL

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