Description：

Leupeptin Hemisulfate is a reversible inhibitor of serine and cysteine proteases. It inhibits cathepsin B (Ki = 6 nM), calpain (Ki = 10 nM), trypsin (Ki = 35 nM), plasmin (Ki = 3.4 μM), and kallikrein (Ki = 19 μM), and has no effect against chymotrypsin, elastase, renin, or pepsin.

Chemical Information：

Molecular Weight (MW)		475.59
Formula		C20H38N6O4.1/2H2SO4
CAS No.		103476-89-7
Solubility (25°C) *	DMSO	95 mg/mL warmed (199.75 mM)
	Water	95 mg/mL (199.75 mM)
	Alcohol	95 mg/mL (199.75 mM)

Preparing Stock Solutions

Concentration Volume (DMSO) Mass	1 mg	5 mg	10 mg
1 mM	2.1027 mL	10.5133 mL	21.0265 mL
5 mM	0.4205 mL	2.1027 mL	4.2053 mL
10 mM	0.2103 mL	1.0513 mL	2.1027 mL
50 mM	0.0421 mL	0.2103 mL	0.4205 mL

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