Description：

Letrozole is a third generation inhibitor of aromatase with IC50 of 0.07-20 nM in cell-free assays.It has no effect on the plasma levels of 17α-OH progesterone, thyroid-stimulating hormone (TSH), luteinizing hormone (LH), follicle-stimulating hormone (FSH), or androstenedione and does not affect normal urine electrolyte excretion or thyroid function in clinical studies.

Chemical Information：

Molecular Weight (MW)		285.3
Formula		C17H11N5
CAS No.		112809-51-5
Solubility (25°C) *	DMSO	57 mg/mL (199.78 mM)
	Water	Insoluble
	Alcohol	Insoluble

Preparing Stock Solutions

Concentration Volume (DMSO) Mass	1 mg	5 mg	10 mg
1 mM	3.5051 mL	17.5254 mL	35.0508 mL
5 mM	0.7010 mL	3.5051 mL	7.0102 mL
10 mM	0.3505 mL	1.7525 mL	3.5051 mL
50 mM	0.0701 mL	0.3505 mL	0.7010 mL

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