Description：

LDN193189 HCl is the hydrochloride salt of LDN193189, which is a selective BMP signaling inhibitor, and inhibits the transcriptional activity of the BMP type I receptors ALK2 and ALK3 with IC50 of 5 nM and 30 nM in C2C12 cell lines, respectively, 200-fold selectivity for BMP versus TGF-β.

Chemical Information：

Molecular Weight (MW)		442.94
Formula		C25H22N6.HCl
CAS No.		1062368-62-0
Solubility (25°C) *	DMSO	Insoluble
	Water	52 mg/mL (117.39 mM)
	Alcohol	Insoluble

Preparing Stock Solutions

Concentration Volume (DMSO) Mass	1 mg	5 mg	10 mg
1 mM	2.2576 mL	11.2882 mL	22.5764 mL
5 mM	0.4515 mL	2.2576 mL	4.5153 mL
10 mM	0.2258 mL	1.1288 mL	2.2576 mL
50 mM	0.0452 mL	0.2258 mL	0.4515 mL

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