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Description:
LDC1267 is a highly selective TAM kinase inhibitor with IC50 of <5 nM, 8 nM, and 29 nM for Mer, Tyro3, and Axl, respectively. Displays lower activity against Met, Aurora B, Lck, Src, and CDK8.
Chemical Information:
Molecular Weight (MW) 560.55 Formula
C30H26F2N4O5
CAS No. 1361030-48-9 Solubility (25°C) * DMSO 100 mg/mL warmed (178.39 mM) Water Insoluble Alcohol 2 mg/mL warmed (3.56 mM)
Preparing Stock Solutions
Concentration Volume (DMSO) Mass 1 mg 5 mg 10 mg 1 mM 1.7840 mL 8.9198 mL 17.8396 mL 5 mM 0.3568 mL 1.7840 mL 3.5679 mL 10 mM 0.1784 mL 0.8920 mL 1.7840 mL 50 mM 0.0357 mL 0.1784 mL 0.3568 mL
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