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Amphotericin B

Amphotericin B

Catalog Number: CC1792 Rank: comment rank 5

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Description:

Amphotericin B (AmB) is an amphipathic polyene antibiotic which permeabilizes ergosterol-containing membranes.

Chemical Information:

Molecular Weight (MW) 924.08
Formula

 

C47H73NO17

 

CAS No. 1397-89-3
Solubility (25°C) * DMSO 22 mg/mL (23.8 mM)
Water Insoluble
Alcohol Insoluble


Biological Activity:

Targets
IC50
TNKS1 TNKS2
11 nM 4 nM


Preparing Stock Solutions

Concentration Volume (DMSO) Mass 1 mg 5 mg 10 mg
1 mM 1.0822 mL 5.4108 mL 10.8216 mL
5 mM 0.2164 mL 1.0822 mL 2.1643 mL
10 mM 0.1082 mL 0.5411 mL 1.0822 mL
50 mM 0.0216 mL 0.1082 mL 0.2164 mL


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