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A-317491

A-317491

Catalog Number: CC8675 Rank: comment rank 5

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Description:

A-317491 is a novel potent and selective non-nucleotide antagonist of P2X3 and P2X2/3 receptors with Ki values of 22 nM and 9 nM for human P2X3 and P2X2/3 receptors.

Chemical Information:

Molecular Weight (MW) 565.57
Formula

 

C33H27NO8

 

CAS No. 475205-49-3
Solubility (25°C) * DMSO 100 mg/mL (176.81 mM)
Water Insoluble
Alcohol 100 mg/mL (176.81 mM)


Biological Activity:

Targets
IC50
Flt1/4 VEGFR2
5 nM/≤3 nM 0.5 nM


Preparing Stock Solutions

Concentration Volume (DMSO) Mass 1 mg 5 mg 10 mg
1 mM 1.7681 mL 8.8406 mL 17.6813 mL
5 mM 0.3536 mL 1.7681 mL 3.5363 mL
10 mM 0.1768 mL 0.8841 mL 1.7681 mL
50 mM 0.0354 mL 0.1768 mL 0.3536 mL


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