Description：

KU-0063794 is a potent and highly specific dual-mTOR inhibitor of mTORC1 and mTORC2 with IC50 of ~10 nM in cell-free assays; no effect on PI3Ks.

Chemical Information：

Molecular Weight (MW)		465.54
Formula		C25H31N5O4
CAS No.		938440-64-3
Solubility (25°C) *	DMSO	16 mg/mL (34.36 mM)
	Water	Insoluble
	Alcohol	Insoluble

Biological Activity：

Targets IC50

MDM2 13.6 μM

Preparing Stock Solutions

Concentration Volume (DMSO) Mass	1 mg	5 mg	10 mg
1 mM	2.1480 mL	10.7402 mL	21.4804 mL
5 mM	0.4296 mL	2.1480 mL	4.2961 mL
10 mM	0.2148 mL	1.0740 mL	2.1480 mL
50 mM	0.0430 mL	0.2148 mL	0.4296 mL

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