Description：

KRN 633 is an ATP-competitive inhibitor of VEGFR1/2/3 with IC50 of 170 nM/160 nM/125 nM, weakly inhibits PDGFR-α/β and c-Kit, does not block the phosphorylation of FGFR-1, EGFR or c-Met in cell.

Chemical Information：

Molecular Weight (MW)		416.86
Formula		C20H21ClN4O4
CAS No.		286370-15-8
Solubility (25°C) *	DMSO	9 mg/mL (21.58 mM)
	Water	Insoluble
	Alcohol	Insoluble

Preparing Stock Solutions

Concentration Volume (DMSO) Mass	1 mg	5 mg	10 mg
1 mM	2.3989 mL	11.9944 mL	23.9889 mL
5 mM	0.4798 mL	2.3989 mL	4.7978 mL
10 mM	0.2399 mL	1.1994 mL	2.3989 mL
50 mM	0.0480 mL	0.2399 mL	0.4798 mL

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