Description：

Kartogenin is an activator of the smad4/smad5 pathway, and promotes the selective differentiation of multipotent mesenchymal stem cells into chondrocytes.

Chemical Information：

Molecular Weight (MW)		317.34
Formula		C20H15NO3
CAS No.		4727-31-5
Solubility (25°C) *	DMSO	63 mg/mL (198.52 mM)
	Water	Insoluble
	Alcohol	5 mg/mL warmed (15.75 mM)

Biological Activity：

Targets IC50

TNF-α PDE4 77 nM 74 nM

Preparing Stock Solutions

Concentration Volume (DMSO) Mass	1 mg	5 mg	10 mg
1 mM	3.1512 mL	15.7560 mL	31.5119 mL
5 mM	0.6302 mL	3.1512 mL	6.3024 mL
10 mM	0.3151 mL	1.5756 mL	3.1512 mL
50 mM	0.0630 mL	0.3151 mL	0.6302 mL

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