Description：

K02288 is a potent, and selective type I BMP receptor inhibitor with IC50 of 1.1, 1.8, 6.4 nM for ALK2, ALK1 and ALK6, showing weaker inhibition on other ALKs (3, 4, 5) and ActRIIA.

Chemical Information：

Molecular Weight (MW)		352.38
Formula		C20H20N2O4
CAS No.		1431985-92-0
Solubility (25°C) *	DMSO	70 mg/mL (198.64 mM)
	Water	Insoluble
	Alcohol	Insoluble

Biological Activity：

Targets IC50

PPARα 1.5 μM (EC50) [

Preparing Stock Solutions

Concentration Volume (DMSO) Mass	1 mg	5 mg	10 mg
1 mM	2.8378 mL	14.1892 mL	28.3785 mL
5 mM	0.5676 mL	2.8378 mL	5.6757 mL
10 mM	0.2838 mL	1.4189 mL	2.8378 mL
50 mM	0.0568 mL	0.2838 mL	0.5676 mL

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