Description：

JNJ-38877605 is an ATP-competitive inhibitor of c-Met with IC50 of 4 nM, 600-fold selective for c-Met than 200 other tyrosine and serine-threonine kinases. Phase 1.

Chemical Information：

Molecular Weight (MW)		377.35
Formula		C19H13F2N7
CAS No.		943540-75-8
Solubility (25°C) *	DMSO	37 mg/mL (98.05 mM)
	Water	Insoluble
	Alcohol	Insoluble

Biological Activity：

Targets IC50

FLT3 42 nM

Preparing Stock Solutions

Concentration Volume (DMSO) Mass	1 mg	5 mg	10 mg
1 mM	2.6501 mL	13.2503 mL	26.5006 mL
5 mM	0.5300 mL	2.6501 mL	5.3001 mL
10 mM	0.2650 mL	1.3250 mL	2.6501 mL
50 mM	0.0530 mL	0.2650 mL	0.5300 mL

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