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Description:
JNJ-1661010 is a potent and selective FAAH inhibitor with IC50 of 10 nM (rat) and 12 nM (human), exhibits >100-fold selectivity for FAAH-1 when compared to FAAH-2.
Chemical Information:
Molecular Weight (MW) 365.45 Formula
C19H19N5OS
CAS No. 681136-29-8 Solubility (25°C) * DMSO 36 mg/mL (98.5 mM) Water Insoluble Alcohol Insoluble
Biological Activity:
Targets IC50
5-HT1A 5-HT7 SERT 5-HT3A 5-HT1B 15 nM 19 nM 1.6 nM 3.7 nM 33 nM
Preparing Stock Solutions
Concentration Volume (DMSO) Mass 1 mg 5 mg 10 mg 1 mM 2.7364 mL 13.6818 mL 27.3635 mL 5 mM 0.5473 mL 2.7364 mL 5.4727 mL 10 mM 0.2736 mL 1.3682 mL 2.7364 mL 50 mM 0.0547 mL 0.2736 mL 0.5473 mL
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