Description：

Ixabepilone is an orally bioavailable microtubule inhibitor. It binds to tubulin and promotes tubulin polymerization and microtubule stabilization, thereby arresting cells in the G2-M phase of the cell cycle and inducing tumor cell apoptosis.

Chemical Information：

Molecular Weight (MW)		506.70
Formula		C27H42N2O5S
CAS No.		219989-84-1
Solubility (25°C) *	DMSO	100 mg/mL (197.35 mM)
	Water	Insoluble
	Alcohol	100 mg/mL (197.35 mM)

Biological Activity：

Targets IC50

HT2B 3.4 nM

Preparing Stock Solutions

Concentration Volume (DMSO) Mass	1 mg	5 mg	10 mg
1 mM	1.9736 mL	9.8678 mL	19.7355 mL
5 mM	0.3947 mL	1.9736 mL	3.9471 mL
10 mM	0.1974 mL	0.9868 mL	1.9736 mL
50 mM	0.0395 mL	0.1974 mL	0.3947 mL

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