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Istradefylline

Istradefylline

Catalog Number: CC2946 Rank: comment rank 5

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Description:

Istradefylline is a selective adenosine A2A receptor (A2AR) antagonist with Ki of 2.2 nM. Phase 3.

Chemical Information:

Molecular Weight (MW) 384.43
Formula

 

C20H24N4O4

 

CAS No. 155270-99-8
Solubility (25°C) * DMSO 6 mg/mL (15.6 mM)
Water Insoluble
Alcohol Insoluble


Biological Activity:

Targets
IC50
B-Raf PDGFRβ Raf-1 VEGFR2
22 nM 57 nM 6 nM 90 nM


Preparing Stock Solutions

Concentration Volume (DMSO) Mass 1 mg 5 mg 10 mg
1 mM 2.6013 mL 13.0063 mL 26.0125 mL
5 mM 0.5203 mL 2.6013 mL 5.2025 mL
10 mM 0.2601 mL 1.3006 mL 2.6013 mL
50 mM 0.0520 mL 0.2601 mL 0.5203 mL


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