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Description:
Istradefylline is a selective adenosine A2A receptor (A2AR) antagonist with Ki of 2.2 nM. Phase 3.
Chemical Information:
Molecular Weight (MW) 384.43 Formula
C20H24N4O4
CAS No. 155270-99-8 Solubility (25°C) * DMSO 6 mg/mL (15.6 mM) Water Insoluble Alcohol Insoluble
Biological Activity:
Targets IC50
B-Raf PDGFRβ Raf-1 VEGFR2 22 nM 57 nM 6 nM 90 nM
Preparing Stock Solutions
Concentration Volume (DMSO) Mass 1 mg 5 mg 10 mg 1 mM 2.6013 mL 13.0063 mL 26.0125 mL 5 mM 0.5203 mL 2.6013 mL 5.2025 mL 10 mM 0.2601 mL 1.3006 mL 2.6013 mL 50 mM 0.0520 mL 0.2601 mL 0.5203 mL
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