Description：

IPA-3 is a selective non-ATP competitive Pak1 inhibitor with IC50 of 2.5 μM in a cell-free assay, no inhibition to group II PAKs (PAKs 4-6).

Chemical Information：

Molecular Weight (MW)		350.45
Formula		C20H14O2S2
CAS No.		42521-82-4
Solubility (25°C) *	DMSO	70 mg/mL (199.74 mM)
	Water	Insoluble
	Alcohol	7 mg/mL (19.97 mM)

Biological Activity：

Targets IC50

JMJD2A JMJD2E JMJD2B JMJD3 JARID1A JMJD2D 445 nM 340 nM 435 nM 855 nM 230 nM 290 nM

Preparing Stock Solutions

Concentration Volume (DMSO) Mass	1 mg	5 mg	10 mg
1 mM	2.8535 mL	14.2674 mL	28.5347 mL
5 mM	0.5707 mL	2.8535 mL	5.7069 mL
10 mM	0.2853 mL	1.4267 mL	2.8535 mL
50 mM	0.0571 mL	0.2853 mL	0.5707 mL

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