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Indole-3-carbinol

Indole-3-carbinol

Catalog Number: CC2469 Rank: comment rank 5

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Description:

Indole-3-carbinol is produced by the breakdown of the glucosinolate glucobrassicin, which can be found at relatively high levels in cruciferous vegetables. Indole-3-carbinol suppresses NF-κB and IκBα kinase activation.

Chemical Information:

Molecular Weight (MW) 147.18
Formula

 

C9H9NO

 

CAS No. 700-06-1
Solubility (25°C) * DMSO 29 mg/mL (197.03 mM)
Water 7 mg/mL (47.56 mM)
Alcohol 29 mg/mL (197.03 mM)


Biological Activity:

Targets
IC50
BRD9 BRD4 BRD2 CECR2
0.122 μM 0.29 μM 0.41 μM 0.017 μM


Preparing Stock Solutions

Concentration Volume (DMSO) Mass 1 mg 5 mg 10 mg
1 mM 6.7944 mL 33.9720 mL 67.9440 mL
5 mM 1.3589 mL 6.7944 mL 13.5888 mL
10 mM 0.6794 mL 3.3972 mL 6.7944 mL
50 mM 0.1359 mL 0.6794 mL 1.3589 mL


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