Description：

Imatinib Mesylate (STI571) is an orally bioavailability mesylate salt of Imatinib, which is a multi-target inhibitor of v-Abl, c-Kit and PDGFR with IC50 of 0.6 μM, 0.1 μM and 0.1 μM in cell-free or cell-based assays, respectively.

Chemical Information：

Molecular Weight (MW)		589.71
Formula		C29H31N7O.CH4SO3
CAS No.		220127-57-1
Solubility (25°C) *	DMSO	118 mg/mL (200.09 mM)
	Water	118 mg/mL (200.09 mM)
	Alcohol	Insoluble

Biological Activity：

Targets IC50

β-tubulin 2.4 μM

Preparing Stock Solutions

Concentration Volume (DMSO) Mass	1 mg	5 mg	10 mg
1 mM	1.6957 mL	8.4787 mL	16.9575 mL
5 mM	0.3391 mL	1.6957 mL	3.3915 mL
10 mM	0.1696 mL	0.8479 mL	1.6957 mL
50 mM	0.0339 mL	0.1696 mL	0.3391 mL

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