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Description:
Ilomastat (GM6001, Galardin) is a broad spectrum matrix metalloprotease (MMP) inhibitor for MMP-1, MMP-2, MMP-3, MMP-7, MMP-8, MMP-9, MMP-12, MMP-14, and MMP-26 with Ki of 0.4 nM, 0.5 nM, 27 nM, 3.7 nM, 0.1 nM, 0.2 nM, 3.6 nM, 13.4 nM, 0.36 nM, respectively.
Chemical Information:
Molecular Weight (MW) 388.46 Formula
C20H28N4O4
CAS No. 142880-36-2 Solubility (25°C) * DMSO 78 mg/mL (200.79 mM) Water Insoluble Alcohol 8 mg/mL warmed (20.59 mM)
Preparing Stock Solutions
Concentration Volume (DMSO) Mass 1 mg 5 mg 10 mg 1 mM 2.5743 mL 12.8713 mL 25.7427 mL 5 mM 0.5149 mL 2.5743 mL 5.1485 mL 10 mM 0.2574 mL 1.2871 mL 2.5743 mL 50 mM 0.0515 mL 0.2574 mL 0.5149 mL
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